Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917.3 It is currently indicated as an immediate release product for moderate to severe pain and as an extended-release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period. Label The first oxycodone containing product, Percodan, was approved by the FDA on April 12, 1950.5
SIZE GUIDE
SIZE | XS | S | M | L | XL | XXL |
---|---|---|---|---|---|---|
BUST | 88 | 89 | 90 | 91 | 92 | 93 |
WAIST | 55 | 56 | 58 | 59 | 62 | 65 |
HIPS | 90 | 92 | 94 | 95 | 96 | 98 |
SIZE | XS | S | M | L | XL | XXL |
---|---|---|---|---|---|---|
BUST | 60 | 62 | 65 | 66 | 68 | 69 |
WAIST | 50 | 55 | 58 | 62 | 65 | 66 |
HIPS | 80 | 82 | 85 | 86 | 88 | 89 |
Size | US | UK / AUS | France | Italy | Japan | Denmark |
---|---|---|---|---|---|---|
XS | 0-2 | 6 | 34 | 38 | 5 | 32 |
S | 2-4 | 8 | 36 | 40 | 7 | 34 |
M | 6-8 | 10 | 38 | 42 | 9 | 36 |
L | 8-10 | 12 | 40 | 44 | 11 | 38 |
Description
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What is Oxycodone?
Buy Oxycodone Online Oxycodone is a powerful prescription opioid medication used to manage moderate to severe pain. Commonly sold under brand names like OxyContin, it is available in both immediate-release and extended-release formulations. Originally developed in Germany in 1917 from thebaine, oxycodone remains a widely prescribed analgesic — but also a substance with a high potential for abuse and addiction.
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Medical Use of Oxycodone
When is it prescribed?
Oxycodone is typically prescribed for:
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Severe chronic pain (e.g., cancer, post-surgical pain, injury)
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Acute pain episodes not relieved by other medications
Oxycodone works by acting on the brain and nervous system to alter the way your body perceives pain. It belongs to a class of drugs known as opioid (narcotic) analgesics.
How to Take Oxycodone
Usage Guidelines
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Extended-release tablets should be swallowed whole — never chewed, crushed, or broken.
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Do not pre-soak or wet the tablet before consuming.
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Always take exactly as prescribed by your doctor to avoid serious health risks, including overdose.
Common Side Effects
Oxycodone, like all opioids, may cause side effects such as:
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Nausea and vomiting
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Drowsiness or fatigue
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Constipation or diarrhea
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Sweating or teary eyes
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Depression or mood changes
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Respiratory issues with higher doses
Storage Instructions
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Store at room temperature, away from light and moisture.
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Keep out of reach of children and pets.
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Do not flush unused medication unless instructed. Consult your pharmacist or local disposal program.
Drug Interactions
Oxycodone can interact with:
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Other opioid painkillers
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Alcohol or sedatives
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Drugs such as naltrexone, pentazocine, or nalbuphine
Always inform your doctor of any medications or supplements you’re using.
How It Works – Mechanism of Action
Oxycodone binds to mu-opioid receptors in the central nervous system, altering pain perception. It:
-
Inhibits neurotransmitter release
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Lowers intracellular cAMP
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Reduces excitability of neurons
This leads to pain relief but also sedation, respiratory depression, and other central nervous effects.
Toxicity and Overdose Risk
Signs of overdose include:
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Slow or shallow breathing
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Extreme drowsiness or coma
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Cold, clammy skin
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Low heart rate and blood pressure
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Death in severe cases
Seek emergency help if an overdose is suspected.
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FAQs
1. What is the difference between immediate-release and extended-release oxycodone?
Immediate-release oxycodone is designed for short-term pain relief, while extended-release oxycodone is intended for long-term management of chronic pain, providing a continuous release of the medication over time.
2. How can I reduce the risk of addiction to oxycodone?
To reduce the risk of addiction, always follow your doctor’s prescribed dosage, avoid taking higher doses or more frequent doses than instructed, and never share your medication with others. If you feel any signs of dependency, speak to your healthcare provider immediately.
3. What should I do if I miss a dose?
If you miss a dose of oxycodone, take it as soon as you remember unless it’s almost time for your next dose. Do not take two doses at the same time to make up for a missed one.
4. Can I take oxycodone with other medications?
Oxycodone can interact with several medications. Always inform your doctor of any other medications you’re taking, including over-the-counter drugs and supplements, to avoid serious drug interactions.
5. What should I do if I suspect an overdose?
If you suspect an overdose, seek emergency medical help immediately. Overdose symptoms include slow breathing, extreme drowsiness, and loss of consciousness.
Disclaimer: Oxycodone is a controlled substance and should only be used under the direction of a licensed healthcare provider. Misuse can lead to addiction, overdose, or death.
Additional information
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