$225.74$670.21

(123 customer reviews)

Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917.3 It is currently indicated as an immediate release product for moderate to severe pain and as an extended-release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period. Label The first oxycodone containing product, Percodan, was approved by the FDA on April 12, 1950.5

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SIZE GUIDE

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JEANS
SIZEXSSMLXLXXL
BUST888990919293
WAIST555658596265
HIPS909294959698
T-SHIRTS
SIZEXSSMLXLXXL
BUST606265666869
WAIST505558626566
HIPS808285868889
Delivery and return
Delivery and return
RETURN POLICYWe do not offer refunds at this time. Organic by John Patrick offers exchanges or store credit only within 10 days upon receipt of goods. All discounted items are final sale, no exchanges. FOR EXCHANGES ONLYKindly, be as considerate as possible when it comes to exchanges. Items must be in original packaging, unused condition with original tags intact. We will ship you the exchanged items if they are available or you will be sent an electronic gift card. Any exchange requests falling outside of the 10 day time frame outlined above will not be accepted. Items returned without a return authorization will be refused. SALE PURCHASESALL SALE ITEMS ARE FINAL SALE. NO RETURNS OR EXCHANGES. INTERNATIONAL PURCHASESINTERNATIONAL SALES ARE FINAL SALE. NO RETURNS OR EXCHANGES. When shipping to international addresses, you will be responsible for import duties, fees and taxes upon delivery of your international order. This charge is determined by your local customs authority. We suggest contacting your local customs office for additional information on these charges.
Shipping Information
Shipping Information
Free Standard Shipping on Domestic (United States) orders. Free International Shipping on orders over $300.00. All International Orders must pay all custom and clearance related duties and taxes. Failure to do so will forfeit your ability to return your order. 2nd Day Air ($50) and Overnight ($100) is available to the continental US, must be placed before 1:30PM Eastern Time on a business day or it will ship out the next business day. International shipping for minimum orders of $150.00 is available for $50.00. We ship using UPS Express Saver for International shipping. Most orders are shipped by the next business day after they are placed. We will send you a shipping confirmation email to your provided email address when all or part of your order is shipped, which will include the tracking number. Domestic orders usually deliver within 5-7 business days. International orders usually deliver within 7-14 business days.
Composition and care
Composition and care
Size US UK / AUS France Italy Japan Denmark
XS 0-2 6 34 38 5 32
S 2-4 8 36 40 7 34
M 6-8 10 38 42 9 36
L 8-10 12 40 44 11 38

Description

What is oxycodone?

Buy Oxycodone, sold under the brand name OxyContin among others, is an opioid medication used for treatment of moderate to severe pain, and a common drug of abuse. It is usually taken by mouth, and is available in immediate-release and controll-release formulations.

Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917.3 It is currently indicate as an immediate release product for moderate to severe pain and as an extended-release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period. Label The first oxycodone containing product, Percodan, was approved by the FDA on April 12, 1950.5, Buy Oxycodone  Online Shop today with Trippy Pharma

Oxycodone is most conventionally embrace by specialists to reduce directly genuine pain distress. Nevertheless, there’s expanding worry among medicinal experts over the risks of using these medications, especially when they are used for a long time.

Uses: 

Oxycodone helps relieve moderate to severe pain.
Oxycodone belongs to a class of drugs known as opioid (narcotic) analgesics.
It works in the brain to change how your body feels and responds to pain.

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Side Effects 

Nausea and vomiting.
Fatigue.
Depression.
Coughing.
Diarrhea.
Runny nose.
Teary eyes.
Sweating.

Storage:

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. See also Warning section. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it expires or no longer useful. For more details, read the Medication Guide, or consult your pharmacist or local waste disposal company.

Medical interactions:

The Medication interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval. Some products that may interact with this drug include certain pain medications (mixed opioid agonist/antagonists such as pentazocine, nalbuphine, butorphanol), naltrexone.

Mechanism Action:

Oxycodone acts as a weak agonist at mu, kappa, and delta-opioid receptors within the central nervous system (CNS). Oxycodone primarily affects mu-type opioid receptors, which are couple with G-protein receptors and function as modulators, both positive and negative, of synaptic transmission via G-proteins that activate effector proteins.

Binding of the opiate stimulates the exchange of GTP for GDP on the G-protein complex. As the effector system is adenylate cyclase and CAMP located at the inner surface of the plasma membrane, opioids decrease intracellular cAMP by inhibiting adenylate cyclase.

Subsequently, the release of nociceptive neurotransmitters such as substance P, GABA, dopamine, acetylcholine, and noradrenaline is inhibit. Opioids such as oxycodone also inhibit the release of vasopressin, somatostatin, insulin, and glucagon.

Opioids close N-type voltage-operated calcium channels (kappa-receptor agonist) and open calcium-dependent inwardly rectifying potassium channels (mu and delta receptor agonist). This results in hyperpolarization and reduced neuronal excitability.

Toxicity:

Symptoms of overdose include respiratory depression, somnolence progressing to stupor or coma, skeletal muscle flaccidity, cold and clammy skin, constricted pupils, bradycardia, hypotension, and death.

HOW SHOULD I TAKE OXYCODONE :

If you are taking the Oxycodone extended-release tablets, swallow them whole; do not chew, break, divide, crush, or dissolve them. Do not presoak, lick or otherwise wet the tablet prior to placing in the mouth. Swallow each tablet right after you put it in your mouth.

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Additional information

quantity

60 pills, 90 pills, 120 pills, 180 pils, 240 pills

Reviews

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